Cloprostenol is used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (±)-Cloprostenol (sodium salt) is manufactured at Cayman Pharma, our Czech subsidiary. The DMF for (±)-Cloprostenol (sodium salt) is on file with the US FDA, Canada, Russia, and the ASMF for (±)-Cloprostenol (sodium salt) is on file in several EU member states and many other countries.