EU Based CDMO Partner for Custom API Development
Cayman Pharma is a European-based Contract Development and Manufacturing Organization (CDMO) specializing in complex, custom Active Pharmaceutical Ingredients (APIs). We support pharmaceutical companies from early route design through clinical supply and commercial manufacturing, with strong analytical and regulatory capabilities under GMP. Our CDMO model is focused on technically demanding APIs, where chemical complexity, containment, and process know-how are more critical than production volume.
Our Mission
Our mission is to deliver high-quality, regulatory-compliant API solutions, from innovative route design to reliable clinical and specialized commercial supply. We combine deep synthetic know-how with hands-on regulatory experience to reduce development risk and accelerate time to market.
After decades of experience in prostaglandin manufacturing, our proven expertise has paved the way to tailored CDMO solutions. We are recognized for our ability to develop and execute challenging multistep chemical syntheses, including high-potency and highly regulated APIs, with full lifecycle support.
“Precise science for global health.”
Whom We Support
Pharmaceutical Companies
Secure and flexible API supply for early development, IND/IMPD, and clinical programs
Robust process development with scalability considered from the outset
Strong confidentiality, IP protection, and regulatory alignment
Development of novel, patent-free synthetic routes
Companies with specialized chemistry requirements
Low- to medium-scale non-GMP precursor synthesis
Custom tailoring of complex, high-value chemical intermediates
API Development & Manufacturing
01
OEB 4/5 Containment
High-potency API development and manufacturing
02
Clinical Trials Supply
APIs for clinical trials and niche or specialized commercial products
03
Process Scale-up
Scale-up from laboratory scale to kilogram-level production, aligned with glass-reactor technologies and high-containment requirements
Process & Technology Support
Tech Transfer
Technology transfer within clearly defined and realistic scale boundaries.
Process Optimization
Process optimization focused on robustness, impurity control, and reproducibility.
Process Validation
Process validation and commercial process verification for low- to medium-volume applications
Our Unique Capabilities
OEB 4 APIs
Scalable up to kilogram quantities under strict containment.
OEB 5 APIs
Expert handling up to hundreds of grams for high-potency drugs.
20+ Step Synthesis
Capability to manage long and highly complex synthetic routes.
Molecules < 1000 Da
Specialized in small molecules with high structural complexity.
Cryogenic Conditions
Stable reaction environments from -70 °C to +100 °C.
High-Pressure
Specialized hydrogenation capabilities for challenging reductions.
Enantioselective
Advanced separations to achieve high chiral purity.
Regulatory Precision
Full alignment with global pharmaceutical standards.
Analytical Development & GMP Control
ICH-compliant development
Impurity profiling
Stability studies
Regulatory Hands-On Support
DMF/CEP preparation
Global submission support
IMPD dossier
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