Superphan
Product Name
| Alternative name |
10% ethanolic solution of (+)-Cloprostenol |
| Chemical name |
(+)-9α,11α,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid |
| CAS number |
54276-21-0 |
Formula
| Formula |
C22H29O6Cl |
| Relative molecular weight |
424.92 |
| Structure |
|
Physiochemical data
Superphan is a clear, colorless to slightly yellowish liquid. The solution contains approximately 10% of biologically active substance (+)-Cloprostenol in ethanol.
| Solubility |
| Ethanol |
very soluble |
| Acetone |
very soluble |
| Chloroform |
soluble |
| Ethyl ether |
slightly soluble |
| Water |
very slightly soluble |
|
Principal analytical parameters
| Concentration |
9.0 - 11.0% w/w |
| Purity (HPLC) |
|
| (+)-Cloprostenol |
min. 97.5% rel. |
| 15S-(+)-cloprostenol |
max. 0.3% rel. |
| 5,6-trans-(+)-cloprostenol |
max. 2.0% rel. |
| Other impurities single |
max. 0.1% rel. |
| Other impurities total |
max. 0.3% rel. |
| Optical rotation |
[α]D25 = +20° to +25° (c=1, ethanol) |
Product quality complies EP 2002 for category 2 and 3A of non-sterile products. Complete specification is available upon request.
Storage and stability
The product is stored in a freezer at temperatures below -18°C in a dry and dark place. Retest time is 18 months in immediate packaging (bottle DURAN of borosilicate glass fitted with PP closure and seal ring) under these conditions.
Use
Superphan is a 10% ethanolic solution of (+)-Cloprostenol. Cloprostenol is used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses
